Open AccessProximity to Parental Symptom Onset and Amyloid-β Burden in Sporadic Alzheimer Disease
Author(s) -
Sylvia Villeneuve,
Jacob W. Vogel,
Julie Gonneaud,
Alexa Pichet Binette,
Pedro RosaNeto,
Serge Gauthier,
Randall J. Bateman,
Anne M. Fagan,
John C. Morris,
Tammie L.S. Benzinger,
Sterling C. Johnson,
John C.S. Breitner,
Judes Poirier
Publication year - 2018
Publication title -
jama neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.298
H-Index - 231
eISSN - 2168-6157
pISSN - 2168-6149
DOI - 10.1001/jamaneurol.2017.5135
Subject(s) - asymptomatic , cohort , medicine , dementia , disease , alzheimer's disease , cohort study , family history , pittsburgh compound b , pediatrics
Alzheimer disease (AD) develops during several decades. Presymptomatic individuals might be the best candidates for clinical trials, but their identification is challenging because they have no symptoms.
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