Association Between Amyloid and Tau Accumulation in Young Adults With Autosomal Dominant Alzheimer Disease
Author(s) -
Yakeel T. Quiroz,
Reisa A. Sperling,
Daniel Norton,
Ana Baena,
Joseph F. ArboledaVelásquez,
Danielle M. Cosio,
Aaron P. Schultz,
Molly R. LaPoint,
Edmarie GuzmánVélez,
John B. Miller,
Leo A. Kim,
Kewei Chen,
Pierre N. Tariot,
Francisco Lopera,
Eric M. Reiman,
Keith A. Johnson
Publication year - 2018
Publication title -
jama neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.298
H-Index - 231
eISSN - 2168-6157
pISSN - 2168-6149
DOI - 10.1001/jamaneurol.2017.4907
Subject(s) - pittsburgh compound b , psen1 , presenilin , standardized uptake value , alzheimer's disease , positron emission tomography , neuroimaging , dementia , psychology , cerebellum , neuroscience , medicine , disease , pathology
It is critically important to improve our ability to diagnose and track Alzheimer disease (AD) as early as possible. Individuals with autosomal dominant forms of AD can provide clues as to which and when biological changes are reliably present prior to the onset of clinical symptoms.
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