Large Perivascular Spaces Visible on Magnetic Resonance Imaging, Cerebral Small Vessel Disease Progression, and Risk of Dementia | Zendy

Jie Ding | Zendy; Sigurður Sigurðsson | Zendy; Pálmi V. Jónsson | Zendy; Guðný Eiríksdóttir | Zendy; Andreas Charidimou | Zendy; Oscar L. López | Zendy; Mark A. van Buchem | Zendy; Vilmundur Guðnason | Zendy; Lenore J. Launer | Zendy

Open Access

Large Perivascular Spaces Visible on Magnetic Resonance Imaging, Cerebral Small Vessel Disease Progression, and Risk of Dementia

Author(s) -

Jie Ding,

Sigurður Sigurðsson,

Pálmi V. Jónsson,

Guðný Eiríksdóttir,

Andreas Charidimou,

Oscar L. López,

Mark A. van Buchem,

Vilmundur Guðnason,

Lenore J. Launer

Publication year - 2017

Publication title -

jama neurology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.298

H-Index - 231

eISSN - 2168-6157

pISSN - 2168-6149

DOI - 10.1001/jamaneurol.2017.1397

Subject(s) - hyperintensity , dementia , magnetic resonance imaging , medicine , neuropsychology , cardiology , cognitive decline , fluid attenuated inversion recovery , cognition , audiology , psychology , disease , radiology , psychiatry

With advancing age, an increased visibility of perivascular spaces (PVSs) on magnetic resonance imaging (MRI) is hypothesized to represent impaired drainage of interstitial fluid from the brain and may reflect underlying cerebral small vessel disease (SVD). However, whether large perivascular spaces (L-PVSs) (>3 mm in diameter) visible on MRI are associated with SVD and cognitive deterioration in older individuals is unknown.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research