Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases | Zendy

Aree Witoelar | Zendy; Iris E. Jansen | Zendy; Yunpeng Wang | Zendy; Joshua Shulman | Zendy; J. Raphael Gibbs | Zendy; Cornelis Blauwendraat | Zendy; Wesley K. Thompson | Zendy; Dena G. Hernandez | Zendy; Srdjan Djurovic | Zendy; Andrew J. Schork | Zendy; Francesco Bettella | Zendy; David Ellinghaus | Zendy; Andre Franke | Zendy; Benedicte A. Lie | Zendy; Linda K. McEvoy | Zendy; Tom H. Karlsen | Zendy; Suzanne Lesage | Zendy; Huw R. Morris | Zendy; Alexis Brice | Zendy; Nicholas Wood | Zendy; Peter Heutink | Zendy; John Hardy | Zendy; Andrew B. Singleton | Zendy; Anders M. Dale | Zendy; Thomas Gasser | Zendy; Ole A. Andreassen | Zendy; Manu Sharma | Zendy

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Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases

Author(s) -

Aree Witoelar,

Iris E. Jansen,

Yunpeng Wang,

Joshua Shulman,

J. Raphael Gibbs,

Cornelis Blauwendraat,

Wesley K. Thompson,

Dena G. Hernandez,

Srdjan Djurovic,

Andrew J. Schork,

Francesco Bettella,

David Ellinghaus,

Andre Franke,

Benedicte A. Lie,

Linda K. McEvoy,

Tom H. Karlsen,

Suzanne Lesage,

Huw R. Morris,

Alexis Brice,

Nicholas Wood,

Peter Heutink,

John Hardy,

Andrew B. Singleton,

Anders M. Dale,

Thomas Gasser,

Ole A. Andreassen,

Manu Sharma

Publication year - 2017

Publication title -

jama neurology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.298

H-Index - 231

eISSN - 2168-6157

pISSN - 2168-6149

DOI - 10.1001/jamaneurol.2017.0469

Subject(s) - genome wide association study , pleiotropy , lrrk2 , genetics , biology , disease , autoimmune disease , genetic association , human leukocyte antigen , phenotype , immunology , single nucleotide polymorphism , medicine , gene , genotype , mutation , antibody , antigen

Recent genome-wide association studies (GWAS) and pathway analyses supported long-standing observations of an association between immune-mediated diseases and Parkinson disease (PD). The post-GWAS era provides an opportunity for cross-phenotype analyses between different complex phenotypes.

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