Association of a Locus in theCAMTA1Gene With Survival in Patients With Sporadic Amyotrophic Lateral Sclerosis | Zendy

Isabella Fogh | Zendy; Kuang Lin | Zendy; Cinzia Tiloca | Zendy; James Rooney | Zendy; Cinzia Gellera | Zendy; Frank P. Diekstra | Zendy; Antonia Ratti | Zendy; Aleksey Shatunov | Zendy; Michael A. van Es | Zendy; Petroula Proitsi | Zendy; Ashley Jones | Zendy; William Sproviero | Zendy; Adriano Chiò | Zendy; Russell L. McLaughlin | Zendy; Gianni Sorarù | Zendy; Lucia Corrado | Zendy; Daniel Ståhl | Zendy; Roberto Del Bo | Zendy; Cristina Cereda | Zendy; Barbara Castellotti | Zendy; Jonathan D. Glass | Zendy; Steven Newhouse | Zendy; Richard Dobson | Zendy; Bradley Smith | Zendy; Simon Topp | Zendy; Wouter van Rheenen | Zendy; Vincent Meininger | Zendy; Judith Melki | Zendy; Karen Morrison | Zendy; Pamela J. Shaw | Zendy; P. Nigel Leigh | Zendy; Peter M. Andersen | Zendy; Giacomo P. Comi | Zendy; Nicola Ticozzi | Zendy; Letizia Mazzini | Zendy; Sandra D’Alfonso | Zendy; Bryan J. Traynor | Zendy; Philip Van Damme | Zendy; Wim Robberecht | Zendy; Robert H. Brown | Zendy; John E. Landers | Zendy; Orla Hardiman | Zendy; Cathryn M. Lewis | Zendy; Leonard H. van den Berg | Zendy; Christopher E. Shaw | Zendy; Jan H. Veldink | Zendy; Vincenzo Silani | Zendy; Ammar AlChalabi | Zendy; John Powell | Zendy

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Association of a Locus in theCAMTA1Gene With Survival in Patients With Sporadic Amyotrophic Lateral Sclerosis

Author(s) -

Isabella Fogh,

Kuang Lin,

Cinzia Tiloca,

James Rooney,

Cinzia Gellera,

Frank P. Diekstra,

Antonia Ratti,

Aleksey Shatunov,

Michael A. van Es,

Petroula Proitsi,

Ashley Jones,

William Sproviero,

Adriano Chiò,

Russell L. McLaughlin,

Gianni Sorarù,

Lucia Corrado,

Daniel Ståhl,

Roberto Del Bo,

Cristina Cereda,

Barbara Castellotti,

Jonathan D. Glass,

Steven Newhouse,

Richard Dobson,

Bradley Smith,

Simon Topp,

Wouter van Rheenen,

Vincent Meininger,

Judith Melki,

Karen Morrison,

Pamela J. Shaw,

P. Nigel Leigh,

Peter M. Andersen,

Giacomo P. Comi,

Nicola Ticozzi,

Letizia Mazzini,

Sandra D’Alfonso,

Bryan J. Traynor,

Philip Van Damme,

Wim Robberecht,

Robert H. Brown,

John E. Landers,

Orla Hardiman,

Cathryn M. Lewis,

Leonard H. van den Berg,

Christopher E. Shaw,

Jan H. Veldink,

Vincenzo Silani,

Ammar AlChalabi,

John Powell

Publication year - 2016

Publication title -

jama neurology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.298

H-Index - 231

eISSN - 2168-6157

pISSN - 2168-6149

DOI - 10.1001/jamaneurol.2016.1114

Subject(s) - amyotrophic lateral sclerosis , proportional hazards model , hazard ratio , genome wide association study , genotype , medicine , locus (genetics) , oncology , genetics , survival analysis , population , age of onset , imputation (statistics) , biology , disease , single nucleotide polymorphism , gene , confidence interval , environmental health , machine learning , missing data , computer science

Amyotrophic lateral sclerosis (ALS) is a devastating adult-onset neurodegenerative disorder with a poor prognosis and a median survival of 3 years. However, a significant proportion of patients survive more than 10 years from symptom onset.

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