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Total Magnetic Resonance Imaging Burden of Small Vessel Disease in Cerebral Amyloid Angiopathy
Author(s) -
Andreas Charidimou,
Sergi MartínezRamírez,
Yaël D. Reijmer,
Jamary OliveiraFilho,
Arne Lauer,
Duangnapa Roongpiboonsopit,
Matthew P. Frosch,
Anastasia Vashkevich,
Alison Ayres,
Jonathan Rosand,
M. Edip Gurol,
Steven M. Greenberg,
Anand Viswanathan
Publication year - 2016
Publication title -
jama neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.298
H-Index - 231
eISSN - 2168-6157
pISSN - 2168-6149
DOI - 10.1001/jamaneurol.2016.0832
Subject(s) - cerebral amyloid angiopathy , superficial siderosis , hyperintensity , medicine , magnetic resonance imaging , neuroimaging , white matter , pathology , brain biopsy , intracerebral hemorrhage , susceptibility weighted imaging , radiology , dementia , disease , surgery , glasgow coma scale , psychiatry
Cerebral amyloid angiopathy (CAA) is characteristically associated with magnetic resonance imaging (MRI) biomarkers of small vessel brain injury, including strictly lobar cerebral microbleeds, cortical superficial siderosis, centrum semiovale perivascular spaces, and white matter hyperintensities. Although these neuroimaging markers reflect distinct pathophysiologic aspects in CAA, no studies to date have combined these structural imaging features to gauge total brain small vessel disease burden in CAA.

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