Time Course and Diagnostic Accuracy of Glial and Neuronal Blood Biomarkers GFAP and UCH-L1 in a Large Cohort of Trauma Patients With and Without Mild Traumatic Brain Injury | Zendy

Linda Papa | Zendy; Gretchen M. Brophy | Zendy; Robert D. Welch | Zendy; Lawrence M. Lewis | Zendy; Carolina F. Braga | Zendy; Ciara N. Tan | Zendy; Neema J. Ameli | Zendy; Marco Antonio López | Zendy; Crystal A. Haeussler | Zendy; Diego I. Mendez Giordano | Zendy; Salvatore Silvestri | Zendy; Philip Giordano | Zendy; Kurt Weber | Zendy; Crystal Hill-Pryor | Zendy; Dallas C. Hack | Zendy

Open Access

Time Course and Diagnostic Accuracy of Glial and Neuronal Blood Biomarkers GFAP and UCH-L1 in a Large Cohort of Trauma Patients With and Without Mild Traumatic Brain Injury

Author(s) -

Linda Papa,

Gretchen M. Brophy,

Robert D. Welch,

Lawrence M. Lewis,

Carolina F. Braga,

Ciara N. Tan,

Neema J. Ameli,

Marco Antonio López,

Crystal A. Haeussler,

Diego I. Mendez Giordano,

Salvatore Silvestri,

Philip Giordano,

Kurt Weber,

Crystal Hill-Pryor,

Dallas C. Hack

Publication year - 2016

Publication title -

jama neurology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.298

H-Index - 231

eISSN - 2168-6157

pISSN - 2168-6149

DOI - 10.1001/jamaneurol.2016.0039

Subject(s) - traumatic brain injury , cohort , medicine , glial fibrillary acidic protein , pathology , neuroscience , psychology , psychiatry , immunohistochemistry

Glial fibrillary acidic protein (GFAP) and ubiquitin C-terminal hydrolase L1 (UCH-L1) have been widely studied and show promise for clinical usefulness in suspected traumatic brain injury (TBI) and concussion. Understanding their diagnostic accuracy over time will help translate them into clinical practice.

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