Neurogranin as a Cerebrospinal Fluid Biomarker for Synaptic Loss in Symptomatic Alzheimer Disease
Author(s) -
Maartje I. Kester,
Charlotte E. Teunissen,
Daniel L. Crimmins,
Elizabeth Herries,
Jack H. Ladenson,
Philip Scheltens,
Wiesje M. van der Flier,
John C. Morris,
David M. Holtzman,
Anne M. Fagan
Publication year - 2015
Publication title -
jama neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.298
H-Index - 231
eISSN - 2168-6157
pISSN - 2168-6149
DOI - 10.1001/jamaneurol.2015.1867
Subject(s) - interquartile range , cerebrospinal fluid , neurogranin , medicine , biomarker , lumbar , cohort , memory clinic , dementia , lumbar puncture , alzheimer's disease , gastroenterology , disease , surgery , biology , biochemistry , protein kinase c , enzyme
Neurogranin (NGRN) seems to be a promising novel cerebrospinal fluid (CSF) biomarker for synaptic loss; however, clinical, and especially longitudinal, data are sparse.
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