Abnormal Functional Brain Connectivity and Personality Traits in Myotonic Dystrophy Type 1
Author(s) -
Laura Serra,
Gabriella Silvestri,
Antonio Petrucci,
Barbara Basile,
Marcella Masciullo,
Elena Makovac,
Mario Torso,
Barbara Spanò,
Chiara Mastropasqua,
Neil A. Harrison,
Maria Laura Ester Bianchi,
Manlio Giacanelli,
Carlo Caltagirone,
Mara Cercignani,
Marco Bozzali
Publication year - 2014
Publication title -
jama neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.298
H-Index - 231
eISSN - 2168-6157
pISSN - 2168-6149
DOI - 10.1001/jamaneurol.2014.130
Subject(s) - default mode network , functional magnetic resonance imaging , personality , resting state fmri , psychology , myotonic dystrophy , personality disorders , borderline personality disorder , big five personality traits , clinical psychology , psychiatry , medicine , neuroscience , social psychology
Myotonic dystrophy type 1 (DM1), the most common muscular dystrophy observed in adults, is a genetic multisystem disorder affecting several other organs besides skeletal muscle, including the brain. Cognitive and personality abnormalities have been reported; however, no studies have investigated brain functional networks and their relationship with personality traits/disorders in patients with DM1.
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