Open AccessDietary ω-3 Polyunsaturated Fatty Acid Intake and Risk for Amyotrophic Lateral Sclerosis
Author(s) -
Kathryn C. Fitzgerald,
Éilis J. O’Reilly,
Guido J. Falcone,
Marjorie L. McCullough,
Yikyung Park,
Laurence N. Kolonel,
Alberto Ascherio
Publication year - 2014
Publication title -
jama neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.298
H-Index - 231
eISSN - 2168-6157
pISSN - 2168-6149
DOI - 10.1001/jamaneurol.2014.1214
Subject(s) - medicine , polyunsaturated fatty acid , cohort , amyotrophic lateral sclerosis , proportional hazards model , cohort study , lower risk , prospective cohort study , relative risk , disease , fatty acid , confidence interval , biology , biochemistry
Amyotrophic lateral sclerosis (ALS) is a severe progressive disease that cannot be prevented or cured. Diet-derived long-chain polyunsaturated fatty acids (PUFAs) are incorporated in brain lipids and modulate oxidative and inflammatory processes and could thus affect ALS risk and progression.
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