Open AccessAssociation of Childhood Fat Mass and Weight With Adult-Onset Type 2 Diabetes in Denmark
Author(s) -
Mohammed T Hudda,
Julie Aarestrup,
Christopher G. Owen,
Derek G. Cook,
Thorkild I. A. Sørensen,
Alicja R. Rudnicka,
Jennifer L. Baker,
Peter H. Whincup,
Claire Nightingale
Publication year - 2021
Publication title -
jama network open
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.278
H-Index - 39
ISSN - 2574-3805
DOI - 10.1001/jamanetworkopen.2021.8524
Subject(s) - medicine , body mass index , cohort , childhood obesity , demography , type 2 diabetes , pediatrics , cohort study , obesity , retrospective cohort study , population , diabetes mellitus , overweight , environmental health , endocrinology , sociology
Key Points Question Is childhood fat mass (FM) more strongly associated with long-term type 2 diabetes (T2D) risk than childhood weight, independent of height? Findings In a population-based cohort study including more than 260 000 schoolchildren in Denmark, there were stronger associations (per kilogram increase) between childhood FM and adult T2D risk, independent of childhood height, than those observed for childhood weight. Meaning Results suggest that weight-based measures, currently used as the basis for childhood obesity assessment in the form of body mass index, were less strongly associated with adult T2D risk than childhood FM.
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