Accuracy of 18-F Fluorodeoxyglucose Positron Emission Tomographic/Computed Tomographic Imaging in Primary Staging of Squamous Cell Carcinoma of the Oral Cavity | Zendy

Christian Linz | Zendy; Roman C. Brands | Zendy; Theresia Herterich | Zendy; Stefan Hartmann | Zendy; Urs MüllerRichter | Zendy; Alexander Kübler | Zendy; Lukas Haug | Zendy; Olivia Kertels | Zendy; Thorsten Alexander Bley | Zendy; Alexander Dierks | Zendy; Andreas K. Buck | Zendy; Constantin Lapa | Zendy; Joachim Brumberg | Zendy

Open Access

Accuracy of 18-F Fluorodeoxyglucose Positron Emission Tomographic/Computed Tomographic Imaging in Primary Staging of Squamous Cell Carcinoma of the Oral Cavity

Author(s) -

Christian Linz,

Roman C. Brands,

Theresia Herterich,

Stefan Hartmann,

Urs MüllerRichter,

Alexander Kübler,

Lukas Haug,

Olivia Kertels,

Thorsten Alexander Bley,

Alexander Dierks,

Andreas K. Buck,

Constantin Lapa,

Joachim Brumberg

Publication year - 2021

Publication title -

jama network open

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.278

H-Index - 39

ISSN - 2574-3805

DOI - 10.1001/jamanetworkopen.2021.7083

Subject(s) - computed tomographic , nuclear medicine , positron emission tomography , fluorodeoxyglucose , positron , medicine , basal cell , positron emission , tomographic reconstruction , radiology , computed tomography , tomography , physics , pathology , quantum mechanics , electron

Key Points Question What is the diagnostic accuracy of 18-F fluorodeoxyglucose positron emission tomographic/computed tomographic imaging in squamous cell carcinoma of the oral cavity for detection of metastases? Findings This diagnostic study including 135 patients showed 83.3% sensitivity, 84.8% specificity, and a negative predictive value of 93.3% with use of 18-F fluorodeoxyglucose positron emission tomographic/computed tomographic imaging for detecting cervical lymph node metastases. The specificity was significantly higher than observed for use of cervical computed tomography and magnetic resonance imaging. Meaning Owing to its high negative predictive value, preoperative 18-F fluorodeoxyglucose positron emission tomographic/computed tomographic imaging may be useful to prevent overtreatment in more than 70% of patients with category T1 to T4 tumors of the oral cavity.

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