Open AccessAssociation of Obesity With Survival Outcomes in Patients With Cancer
Author(s) -
Fausto Petrelli,
Alessio Cortellini,
Alice Indini,
Gianluca Tomasello,
Michele Ghidini,
Olga Nigro,
Massimiliano Salati,
Lorenzo Dottorini,
Alessandro Iaculli,
Antonio Ghidini,
Valentina Rampulla,
Sandro Barni,
Mary Cabiddu,
Antonio Bossi,
Alberto Zaniboni
Publication year - 2021
Publication title -
jama network open
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.278
H-Index - 39
ISSN - 2574-3805
DOI - 10.1001/jamanetworkopen.2021.3520
Subject(s) - medicine , obesity , body mass index , hazard ratio , cancer , meta analysis , guideline , observational study , data extraction , epidemiology , oncology , medline , confidence interval , pathology , political science , law
Key Points Question Is obesity associated with better prognosis in patients with cancer? Findings This meta-analysis of 203 studies with more than 6.3 million participants found that obesity was associated with increased overall and cancer-specific mortality, especially among patients with breast, colon, and uterine cancer. In contrast, patients with obesity and renal cell carcinoma, lung cancer, or melanoma had better survival than patients without obesity. Meaning These findings suggest that survival outcomes are poor among patients with obesity and cancer, except in lung cancer and melanoma.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom