Open AccessAssociation Between Prenatal Exposure to Metals and Atopic Dermatitis Among Children Aged 4 Years in Taiwan
Author(s) -
TsungLin Tsai,
ShuLi Wang,
ChiaJung Hsieh,
HuiJu Wen,
ChinChi Kuo,
HueiJu Liu,
Chien-Wen Sun,
Mei-Lien Chen,
MingTsang Wu,
Ying- Chih Tseng,
ChawLiang Chang,
TsungHo Ying,
PenHua Su,
Kuei-Cheng Hsu,
Hsiao-Neng Chen,
Jian-Wun Cian,
WeiTe Lei,
Sheng-Po Kao,
YuChi Wei,
YuHsun Chang,
FuChen Kuo,
Chien-Yi Wu
Publication year - 2021
Publication title -
jama network open
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.278
H-Index - 39
ISSN - 2574-3805
DOI - 10.1001/jamanetworkopen.2021.31327
Subject(s) - atopic dermatitis , medicine , cohort , pediatrics , cohort study , pregnancy , environmental health , dermatology , genetics , biology
Key Points Question Is prenatal exposure to arsenic and other metals associated with the occurrence of atopic dermatitis in young children? Findings In this cohort study of 586 mother and child pairs, prenatal arsenic exposure was associated with approximately 2.4 times the occurrence of atopic dermatitis in children at age 4 years. In addition, coexposure to arsenic and cadmium was associated with increased odds of developing atopic dermatitis. Meaning The results of this study suggest that prevention of inorganic arsenic and cadmium exposure among pregnant women could reduce the risk of atopic dermatitis and other allergic diseases in children.
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