Open AccessSurveillance for Colonization, Transmission, and Infection With Methicillin-Susceptible Staphylococcus aureus in a Neonatal Intensive Care Unit
Author(s) -
Dennis Nurjadi,
Vanessa M. Eichel,
Patrik Tabatabai,
Sabrina Klein,
Katharina Last,
Nico T. Mutters,
Johannes Pöschl,
Philipp Zanger,
Klaus Heeg,
Sébastien Boutin
Publication year - 2021
Publication title -
jama network open
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.278
H-Index - 39
ISSN - 2574-3805
DOI - 10.1001/jamanetworkopen.2021.24938
Subject(s) - medicine , staphylococcus aureus , neonatal intensive care unit , interquartile range , methicillin resistant staphylococcus aureus , outbreak , odds ratio , transmission (telecommunications) , incidence (geometry) , staphylococcal infections , intensive care unit , pediatrics , virology , biology , electrical engineering , physics , bacteria , genetics , optics , engineering
Key Points Question What are the risk factors for the acquisition of methicillin-susceptible Staphylococcus aureus (MSSA) colonization and infections in a neonatal intensive care unit? Findings In this cohort study of 590 newborns, the acquisition of S aureus colonization and infection was monitored until hospital discharge. Colonization with MSSA was associated with lower birth weight, longer hospitalization, and higher odds of acquiring S aureus infection during hospitalization. Meaning These findings suggest that nasal colonization is a relevant risk factor for MSSA infection in a nonoutbreak neonatal intensive care unit setting.
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