Assessment of All-Cause Cancer Incidence Among Individuals With Preeclampsia or Eclampsia During First Pregnancy

Key Points Question Is the occurrence of preeclampsia or eclampsia during a first pregnancy associated with a future risk of cancer? Findings In this cohort study of 4 322 970 female individuals with and without preeclampsia or eclampsia during their first pregnancy, myelodysplastic syndromes or myeloproliferative diseases and kidney cancer were more common among those who experienced preeclampsia or eclampsia, whereas breast cancer was less common. Meaning The study’s findings suggest that there may be a pathophysiological association between preeclampsia or eclampsia during a first pregnancy and the incidence of some myelodysplastic syndromes or myeloproliferative diseases, kidney cancer, and breast cancer.