Assessment of Cesarean Delivery and Neurodevelopmental and Psychiatric Disorders in the Children of a Population-Based Swedish Birth Cohort | Zendy

Tianyang Zhang | Zendy; Gustaf Brander | Zendy; Ängla Mantel | Zendy; Ralf KujaHalkola | Zendy; Olof Stephansson | Zendy; Zheng Chang | Zendy; Henrik Larsson | Zendy; David MataixCols | Zendy; Lorena Fernández de la Cruz | Zendy

Open Access

Assessment of Cesarean Delivery and Neurodevelopmental and Psychiatric Disorders in the Children of a Population-Based Swedish Birth Cohort

Author(s) -

Tianyang Zhang,

Gustaf Brander,

Ängla Mantel,

Ralf KujaHalkola,

Olof Stephansson,

Zheng Chang,

Henrik Larsson,

David MataixCols,

Lorena Fernández de la Cruz

Publication year - 2021

Publication title -

jama network open

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.278

H-Index - 39

ISSN - 2574-3805

DOI - 10.1001/jamanetworkopen.2021.0837

Subject(s) - medicine , psychiatry , cohort , anxiety , autism , pediatrics , autism spectrum disorder , bipolar disorder , attention deficit hyperactivity disorder , cohort study , confounding , eating disorders , population , cognition , environmental health

Key Points Question Is cesarean delivery associated with neurodevelopmental and psychiatric disorders in children? Findings In this Swedish population-based birth cohort study of more 1.1 million children, births via planned or intrapartum cesarean delivery were associated with a moderately increased risk of neurodevelopmental disorders in children, but these associations were attenuated after adjusting for familial factors. Meaning The association between cesarean delivery and neurodevelopmental disorders may be explained by unmeasured familial confounding; observational studies on the association between prenatal risk factors and child outcomes may be spurious owing to unmeasured confounders.

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