Risk of Depression in the Adolescent and Adult Offspring of Mothers With Perinatal Depression | Zendy

Vaishali Tirumalaraju | Zendy; Robert Suchting | Zendy; Jonathan Evans | Zendy; Laura Goetzl | Zendy; Jerrie Refuerzo | Zendy; Alexander Neumann | Zendy; Deepa Anand | Zendy; Rekha Ravikumar | Zendy; Charles E. Green | Zendy; Philip J. Cowen | Zendy; Sudhakar Selvaraj | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Risk of Depression in the Adolescent and Adult Offspring of Mothers With Perinatal Depression

Author(s) -

Vaishali Tirumalaraju,

Robert Suchting,

Jonathan Evans,

Laura Goetzl,

Jerrie Refuerzo,

Alexander Neumann,

Deepa Anand,

Rekha Ravikumar,

Charles E. Green,

Philip J. Cowen,

Sudhakar Selvaraj

Publication year - 2020

Publication title -

jama network open

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.278

H-Index - 39

ISSN - 2574-3805

DOI - 10.1001/jamanetworkopen.2020.8783

Subject(s) - offspring , depression (economics) , psychology , psychiatry , medicine , developmental psychology , pregnancy , biology , genetics , economics , macroeconomics

Key Points Question Is maternal perinatal depression associated with increased risk of offspring depression in adolescence and adulthood? Findings In this systematic review and meta-analysis that examined 6 prospective longitudinal studies involving 15 584 mother-child dyads, a 70% increase in the odds of adolescent and adult offspring depression was noted among offspring of mothers who had perinatal depression. Meaning In this study, maternal perinatal depression was associated with the risk of depression in adolescence and adulthood among offspring; future studies aimed at exploring the neurobiological mechanism of risk transmission and postinterventional risk reduction could improve the management of depressive disorders.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research