Association of Patient Demographic Characteristics and Insurance Status With Survival in Cancer Randomized Clinical Trials With Positive Findings | Zendy

Joseph M. Unger | Zendy; Charles D. Blanke | Zendy; Michael LeBlanc | Zendy; William E. Barlow | Zendy; Riha Vaidya | Zendy; Scott D. Ramsey | Zendy; Dawn L. Hershman | Zendy

Open Access

Association of Patient Demographic Characteristics and Insurance Status With Survival in Cancer Randomized Clinical Trials With Positive Findings

Author(s) -

Joseph M. Unger,

Charles D. Blanke,

Michael LeBlanc,

William E. Barlow,

Riha Vaidya,

Scott D. Ramsey,

Dawn L. Hershman

Publication year - 2020

Publication title -

jama network open

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.278

H-Index - 39

ISSN - 2574-3805

DOI - 10.1001/jamanetworkopen.2020.3842

Subject(s) - randomized controlled trial , medicine , association (psychology) , oncology , clinical trial , cancer , demography , psychology , sociology , psychotherapist

Key Points Question Do positive treatment effects from cancer clinical trials apply to all sociodemographic groups? Findings In this cohort study using patient-level data recorded for 10 804 patients who participated in cancer randomized clinical trials with positive findings, the receipt of experimental treatment vs standard treatment was associated with improved overall survival among patients 65 years or older compared with patients younger than 65 years. No significant added benefit of experimental treatment was observed among patients having Medicaid or no insurance compared with those with private insurance. Meaning Patients with Medicaid or no insurance may have smaller added benefits from experimental therapies in clinical trials.

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