Open AccessEvaluation of Deviation From Planned Cohort Size and Operating Characteristics of Phase 1 Trials
Author(s) -
Minjeong Park,
Suyu Liu,
Timothy A. Yap,
Ying Yuan
Publication year - 2021
Publication title -
jama network open
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.278
H-Index - 39
ISSN - 2574-3805
DOI - 10.1001/jamanetworkopen.2020.37563
Subject(s) - cohort , medicine , clinical trial , interim , cohort study , interim analysis , statistics , mathematics , archaeology , history
This cross-sectional study evaluates the association of cohort size deviation with the operating characteristics in phase 1 clinical trials using simulation models.
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