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Respiratory and Psychophysical Sequelae Among Patients With COVID-19 Four Months After Hospital Discharge
Author(s) -
Mattia Bellan,
Daniele Soddu,
Piero Emilio Balbo,
Alessio Baricich,
Patrizia Zeppegno,
Gian Carlo Avanzi,
Giulia Baldon,
Giuseppe Bartolomei,
Marco Battaglia,
Sofia Battistini,
Valeria Binda,
Margherita Beatrice Borg,
Vincenzo Cantaluppi,
Luigi Mario Castello,
Elisa Clivati,
Carlo Cisari,
Martina Costanzo,
Alessandro Croce,
Daria Cuneo,
Carla De Benedittis,
Simona De Vecchi,
A. Feggi,
Martina Gai,
Eleonora Gambaro,
E. Gattoni,
Carla Gramaglia,
Leonardo Grisafi,
C. Guerriero,
Eyal Hayden,
Amalia Jona,
Marco Invernizzi,
Luca Lorenzini,
Lucia Loreti,
María Martelli,
Paolo Marzullo,
Erica Matino,
Antonio Panero,
Elena Parachini,
Filippo Patrucco,
Giuseppe Patti,
Alice Pirovano,
P. Prosperini,
Riccardo Quaglino,
Cristina Rigamonti,
Pier Paolo Sainaghi,
Camilla Vecchi,
Erika Zecca,
Mario Pirisi
Publication year - 2021
Publication title -
jama network open
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.278
H-Index - 39
ISSN - 2574-3805
DOI - 10.1001/jamanetworkopen.2020.36142
Subject(s) - medicine , case fatality rate , pulmonary function testing , cohort study , cohort , diffusing capacity , covid-19 , prospective cohort study , pediatrics , emergency medicine , lung , epidemiology , disease , lung function , infectious disease (medical specialty)
Key Points Question What respiratory, functional, and psychological sequalae are associated with recovery from coronavirus disease 2019 (COVID-19)? Findings In this cohort study of 238 patients with COVID-19 hospitalized in an academic hospital in Northern Italy, more than half of participants had a significant reduction of diffusing lung capacity for carbon monoxide or measurable functional impairment and approximately one-fifth of patients had symptoms of posttraumatic stress 4 months after discharge. Meaning These findings suggest that despite virological recovery, a sizable proportion of patients with COVID-19 experienced respiratory, functional, or psychological sequelae months after hospital discharge.

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