Mortality Among Young Adults Born Preterm and Early Term in 4 Nordic Nations
Author(s) -
Kari Risnes,
Josephine Funck Bilsteen,
Paul D. Brown,
Anna Pulakka,
AnneMarie Nybo Andersen,
Signe Opdahl,
Eero Kajantie,
Sven Sandin
Publication year - 2021
Publication title -
jama network open
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.278
H-Index - 39
ISSN - 2574-3805
DOI - 10.1001/jamanetworkopen.2020.32779
Subject(s) - medicine , hazard ratio , gestational age , pediatrics , population , cohort study , gestation , cause of death , pregnancy , cohort , premature birth , disease , environmental health , confidence interval , biology , genetics
Key Points Question Are all-cause and noncommunicable disease (NCD) mortality risks higher amomg adults born preterm and early term compared with those born at full term? Findings This cohort study of more than 6.1 million individuals from 4 Nordic birth cohorts provided found all degrees of preterm birth and early-term birth are associated with increased risk of premature adult death. Excess mortality associated with shorter gestation was pronounced for death from NCDs, such as cardiovascular diseases, chronic lung disease, and diabetes. Meaning These findings suggest that increased early adult mortality associated with shorter gestation includes excess risk in the large group of adults born late preterm and early term and is pronounced for NCD deaths.
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