Association of Sickle Cell Trait With Incidence of Coronary Heart Disease Among African American Individuals | Zendy

Hyacinth I. Hyacinth | Zendy; Nora Franceschini | Zendy; Samantha R. Seals | Zendy; Marguerite R. Irvin | Zendy; Ninad S. Chaudhary | Zendy; Rakhi P. Naik | Zendy; Álvaro Alonso | Zendy; Cara L. Carty | Zendy; Gregory L. Burke | Zendy; Neil A. Zakai | Zendy; Cheryl A. Winkler | Zendy; Victor A. David | Zendy; Jeffrey B. Kopp | Zendy; Suzanne E. Judd | Zendy; Robert J. Adams | Zendy; Beatrice E. Gee | Zendy; W. T. Longstreth | Zendy; Leonard E. Egede | Zendy; Daniel T. Lackland | Zendy; Charles S. Greenberg | Zendy; Herman A. Taylor | Zendy; JoAnn E. Manson | Zendy; Nigel S. Key | Zendy; Vimal K. Derebail | Zendy; Abhijit V. Kshirsagar | Zendy; Aaron R. Folsom | Zendy; Suma Konety | Zendy; Virginia J. Howard | Zendy; Matthew Allison | Zendy; James G. Wilson | Zendy; Adolfo Correa | Zendy; Degui Zhi | Zendy; Donna K. Arnett | Zendy; George Howard | Zendy; Alexander P. Reiner | Zendy; Mary Cushman | Zendy; Monika M. Safford | Zendy

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Association of Sickle Cell Trait With Incidence of Coronary Heart Disease Among African American Individuals

Author(s) -

Hyacinth I. Hyacinth,

Nora Franceschini,

Samantha R. Seals,

Marguerite R. Irvin,

Ninad S. Chaudhary,

Rakhi P. Naik,

Álvaro Alonso,

Cara L. Carty,

Gregory L. Burke,

Neil A. Zakai,

Cheryl A. Winkler,

Victor A. David,

Jeffrey B. Kopp,

Suzanne E. Judd,

Robert J. Adams,

Beatrice E. Gee,

W. T. Longstreth,

Leonard E. Egede,

Daniel T. Lackland,

Charles S. Greenberg,

Herman A. Taylor,

JoAnn E. Manson,

Nigel S. Key,

Vimal K. Derebail,

Abhijit V. Kshirsagar,

Aaron R. Folsom,

Suma Konety,

Virginia J. Howard,

Matthew Allison,

James G. Wilson,

Adolfo Correa,

Degui Zhi,

Donna K. Arnett,

George Howard,

Alexander P. Reiner,

Mary Cushman,

Monika M. Safford

Publication year - 2021

Publication title -

jama network open

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.278

H-Index - 39

ISSN - 2574-3805

DOI - 10.1001/jamanetworkopen.2020.30435

Subject(s) - medicine , sickle cell trait , incidence (geometry) , population , demography , myocardial infarction , sickle cell anemia , prospective cohort study , disease , environmental health , physics , sociology , optics

Key Points Question Is sickle cell trait associated with increased risk of myocardial infarction and coronary heart disease among African American individuals? Findings In this cohort study of 23 197 African American individuals in 5 cardiovascular epidemiologic studies, sickle cell trait was not associated with increased risk of myocardial infarction or coronary heart disease among African American individuals. Meaning In this study, sickle cell trait was not associated with increased risk of fatal and nonfatal myocardial infarction or coronary heart disease, suggesting that these disorders may not be associated with sickle cell trait–related sudden death.

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