Surgical Delay and Pathological Outcomes for Clinically Localized High-Risk Prostate Cancer | Zendy

Leilei Xia | Zendy; Ruchika Talwar | Zendy; Raju Chelluri | Zendy; Thomas J. Guzzo | Zendy; Daniel J. Lee | Zendy

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Surgical Delay and Pathological Outcomes for Clinically Localized High-Risk Prostate Cancer

Author(s) -

Leilei Xia,

Ruchika Talwar,

Raju Chelluri,

Thomas J. Guzzo,

Daniel J. Lee

Publication year - 2020

Publication title -

jama network open

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.278

H-Index - 39

ISSN - 2574-3805

DOI - 10.1001/jamanetworkopen.2020.28320

Subject(s) - medicine , prostatectomy , prostate cancer , interquartile range , pathological , retrospective cohort study , prostate specific antigen , cohort , biochemical recurrence , surgical margin , laparoscopic radical prostatectomy , urology , cancer , oncology

Key Points Question Is delayed radical prostatectomy for high-risk prostate cancer associated with negative patient outcomes? Findings In this cohort study of 32 184 patients from the US National Cancer Database who underwent radical prostatectomy within 180 days of diagnosis for high-risk prostate cancer, increased surgical delay time was not associated with higher risks of adverse pathological features (pT3-4 disease, node positivity, or positive margin). Meaning These findings suggest that prostate cancer surgery can be safely delayed up to 6 months and should be considered as low priority compared with other emergent and cancer surgeries when health care resources need to be prioritized during special times, such as the coronavirus disease 2019 pandemic.

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