Association of Primary Intracerebral Hemorrhage With Pregnancy and the Postpartum Period | Zendy

Jennifer Meeks | Zendy; Arvind Bambhroliya | Zendy; Katie Alex | Zendy; Sunil A. Sheth | Zendy; Sean I. Savitz | Zendy; Eliza C. Miller | Zendy; Louise D. McCullough | Zendy; Farhaan Vahidy | Zendy

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Association of Primary Intracerebral Hemorrhage With Pregnancy and the Postpartum Period

Author(s) -

Jennifer Meeks,

Arvind Bambhroliya,

Katie Alex,

Sunil A. Sheth,

Sean I. Savitz,

Eliza C. Miller,

Louise D. McCullough,

Farhaan Vahidy

Publication year - 2020

Publication title -

jama network open

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.278

H-Index - 39

ISSN - 2574-3805

DOI - 10.1001/jamanetworkopen.2020.2769

Subject(s) - medicine , pregnancy , poisson regression , obstetrics , postpartum period , population , intracerebral hemorrhage , cohort , cohort study , pediatrics , surgery , glasgow coma scale , genetics , environmental health , biology

Key Points Question What is the population-level risk of intracerebral hemorrhage during pregnancy and an extended postpartum period, and what is the association between this risk and maternal and fetal mortality? Findings This cohort-crossover study of 3 314 945 pregnancies found an increased rate of intracerebral hemorrhage during the third trimester (2.9 vs 0.7 cases per 100 000 pregnancies) and the first 12 postpartum weeks (4.4 vs 0.5 cases per 100 000 pregnancies). Maternal and fetal mortality were higher among women who experienced intracerebral hemorrhage, and age and race disparities were also observed. Meaning These findings suggest that the increased risk of intracerebral hemorrhage into 12 weeks post partum warrants extended postnatal monitoring of high-risk women.

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