Association of the Mediterranean Diet With Onset of Diabetes in the Women’s Health Study | Zendy

Shafqat Ahmad | Zendy; Olga Demler | Zendy; Qi Sun | Zendy; M. Vinayaga Moorthy | Zendy; Chunying Li | Zendy; IMin Lee | Zendy; Paul M. Ridker | Zendy; JoAnn E. Manson | Zendy; Frank B. Hu | Zendy; Tove Fall | Zendy; Daniel I. Chasman | Zendy; Susan Cheng | Zendy; Aruna D. Pradhan | Zendy; Samia Mora | Zendy

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Association of the Mediterranean Diet With Onset of Diabetes in the Women’s Health Study

Author(s) -

Shafqat Ahmad,

Olga Demler,

Qi Sun,

M. Vinayaga Moorthy,

Chunying Li,

IMin Lee,

Paul M. Ridker,

JoAnn E. Manson,

Frank B. Hu,

Tove Fall,

Daniel I. Chasman,

Susan Cheng,

Aruna D. Pradhan,

Samia Mora

Publication year - 2020

Publication title -

jama network open

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.278

H-Index - 39

ISSN - 2574-3805

DOI - 10.1001/jamanetworkopen.2020.25466

Subject(s) - medicine , type 2 diabetes , diabetes mellitus , mediterranean diet , cohort study , cohort , hazard ratio , population , demography , environmental health , endocrinology , confidence interval , sociology

Key Points Question Is the Mediterranean (MED) diet associated with reduced risk of diabetes in a US population, and if so, what are possible underlying biological mechanistic pathways? Findings Among 25 317 women followed up for 20 years in a prospective epidemiological cohort study, 2307 developed type 2 diabetes. Higher baseline MED intake was associated with a 30% reduction in future risk of diabetes; biomarkers of insulin resistance, adiposity, high-density lipoprotein, and inflammation contributed most to explaining this inverse association. Meaning These findings suggest that the MED diet may be protective against diabetes by improving insulin resistance, lipoprotein metabolism, and inflammation.

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