Open AccessAssociation of Maternal Prepregnancy Body Mass Index With Fetal Growth and Neonatal Thalamic Brain Connectivity Among Adolescent and Young Women
Author(s) -
Marisa N. Spann,
Dustin Scheinost,
Tianshu Feng,
Kristiana Barbato,
Seonjoo Lee,
Catherine Monk,
Bradley S. Peterson
Publication year - 2020
Publication title -
jama network open
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.278
H-Index - 39
ISSN - 2574-3805
DOI - 10.1001/jamanetworkopen.2020.24661
Subject(s) - medicine , body mass index , pregnancy , offspring , prospective cohort study , obstetrics , cohort , cohort study , obesity , pediatrics , genetics , biology
Key Points Question Is maternal prepregnancy body mass index among adolescent and young women associated with fetal growth and neonatal functional connectivity? Findings In this cohort study that included 129 pregnant adolescent and young adult women, maternal prepregnancy body mass index had a significant positive association with the slope of estimated fetal weight and with greater local thalamic and lower frontothalamic connectivity. Meaning These findings suggest that maternal prepregnancy body mass index was associated with the regulation of body weight and functional connectivity of the thalamus in newborn infants.
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