Rates of Brain Atrophy Across Disease Stages in Familial Frontotemporal Dementia Associated With MAPT, GRN, and C9orf72 Pathogenic Variants | Zendy

Adam M. Staffaroni | Zendy; ShengYang M. Goh | Zendy; Yann Cobigo | Zendy; Elise Ong | Zendy; Suzee E. Lee | Zendy; Kaitlin B. Casaletto | Zendy; Amy Wolf | Zendy; Leah K. Forsberg | Zendy; Nupur Ghoshal | Zendy; Neill R. GraffRadford | Zendy; Murray Grossman | Zendy; Hilary W. Heuer | Zendy; GingYuek Robin Hsiung | Zendy; Kejal Kantarci | Zendy; David S. Knopman | Zendy; Walter K. Kremers | Zendy; Ian R. Mackenzie | Zendy; Bruce L. Miller | Zendy; Otto Pedraza | Zendy; Katya Rascovsky | Zendy; Maria Carmela Tartaglia | Zendy; Zbigniew K. Wszołek | Zendy; Joel H. Kramer | Zendy; John Kornak | Zendy; Bradley F. Boeve | Zendy; Adam L. Boxer | Zendy; Howard J. Rosen | Zendy

Open Access

Rates of Brain Atrophy Across Disease Stages in Familial Frontotemporal Dementia Associated With MAPT, GRN, and C9orf72 Pathogenic Variants

Author(s) -

Adam M. Staffaroni,

ShengYang M. Goh,

Yann Cobigo,

Elise Ong,

Suzee E. Lee,

Kaitlin B. Casaletto,

Amy Wolf,

Leah K. Forsberg,

Nupur Ghoshal,

Neill R. GraffRadford,

Murray Grossman,

Hilary W. Heuer,

GingYuek Robin Hsiung,

Kejal Kantarci,

David S. Knopman,

Walter K. Kremers,

Ian R. Mackenzie,

Bruce L. Miller,

Otto Pedraza,

Katya Rascovsky,

Maria Carmela Tartaglia,

Zbigniew K. Wszołek,

Joel H. Kramer,

John Kornak,

Bradley F. Boeve,

Adam L. Boxer,

Howard J. Rosen

Publication year - 2020

Publication title -

jama network open

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.278

H-Index - 39

ISSN - 2574-3805

DOI - 10.1001/jamanetworkopen.2020.22847

Subject(s) - frontotemporal lobar degeneration , c9orf72 , frontotemporal dementia , atrophy , clinical dementia rating , dementia , semantic dementia , dementia with lewy bodies , psychology , medicine , disease

This observation study characterizes regions and rates of atrophy in the 3 primary familial frontotemporal lobar degeneration genes ( MAPT , GRN , and C9orf72 ) across all disease stages from asymptomatic to dementia.

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