Association of Vitamin D Status and Other Clinical Characteristics With COVID-19 Test Results | Zendy

David O. Meltzer | Zendy; Thomas J. Best | Zendy; Zhang Hui | Zendy; Tamara Vokes | Zendy; Vineet M. Arora | Zendy; Julian Solway | Zendy

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Association of Vitamin D Status and Other Clinical Characteristics With COVID-19 Test Results

Author(s) -

David O. Meltzer,

Thomas J. Best,

Zhang Hui,

Tamara Vokes,

Vineet M. Arora,

Julian Solway

Publication year - 2020

Publication title -

jama network open

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.278

H-Index - 39

ISSN - 2574-3805

DOI - 10.1001/jamanetworkopen.2020.19722

Subject(s) - medicine , vitamin d and neurology , vitamin d deficiency , incidence (geometry) , covid-19 , retrospective cohort study , vitamin , cohort study , gastroenterology , disease , infectious disease (medical specialty) , physics , optics

Key Points Question Is vitamin D status, reflecting vitamin D levels and treatment, associated with test results for coronavirus disease 2019 (COVID-19)? Findings In this cohort study of 489 patients who had a vitamin D level measured in the year before COVID-19 testing, the relative risk of testing positive for COVID-19 was 1.77 times greater for patients with likely deficient vitamin D status compared with patients with likely sufficient vitamin D status, a difference that was statistically significant. Meaning These findings appear to support a role of vitamin D status in COVID-19 risk; randomized clinical trials are needed to determine whether broad population interventions and interventions among groups at increased risk of vitamin D deficiency and COVID-19 could reduce COVID-19 incidence.

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