Clinical, Bronchoscopic, and Imaging Findings of e-Cigarette, or Vaping, Product Use–Associated Lung Injury Among Patients Treated at an Academic Medical Center | Zendy

Scott K. Aberegg | Zendy; Meghan M. Cirulis | Zendy; Sean D. Maddock | Zendy; Andrew Freeman | Zendy; Lynn M Keenan | Zendy; Cheryl S. Pirozzi | Zendy; Sanjeev Raman | Zendy; Joyce Schroeder | Zendy; Howard Mann | Zendy; Sean J. Callahan | Zendy

Open Access

Clinical, Bronchoscopic, and Imaging Findings of e-Cigarette, or Vaping, Product Use–Associated Lung Injury Among Patients Treated at an Academic Medical Center

Author(s) -

Scott K. Aberegg,

Meghan M. Cirulis,

Sean D. Maddock,

Andrew Freeman,

Lynn M Keenan,

Cheryl S. Pirozzi,

Sanjeev Raman,

Joyce Schroeder,

Howard Mann,

Sean J. Callahan

Publication year - 2020

Publication title -

jama network open

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.278

H-Index - 39

ISSN - 2574-3805

DOI - 10.1001/jamanetworkopen.2020.19176

Subject(s) - medicine , interquartile range , rhinovirus , pneumonia , pediatrics , gastroenterology , respiratory system

Key Points Question What are the typical clinical, radiographic, and bronchoscopic findings and clinical outcomes of e-cigarette, or vaping, product use–associated lung injury (EVALI)? Findings This case series of 31 patients found that EVALI typically presented as a flu-like illness with elevated inflammatory markers and an organizing pneumonia pattern on computed tomography imaging. Bronchoscopy showed lipid-laden macrophages and had a high rate of false-positive results for infection. Meaning The findings of this study suggest that EVALI has a characteristic clinical and radiographic presentation and that bronchoscopy has limited utility in its evaluation.

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