Association of Prehospital Plasma With Survival in Patients With Traumatic Brain Injury | Zendy

Danielle S. Gruen | Zendy; Francis X. Guyette | Zendy; Joshua B. Brown | Zendy; David O. Okonkwo | Zendy; Ava M. Puccio | Zendy; Insiyah Campwala | Zendy; Matthew T. Tessmer | Zendy; Brian J. Daley | Zendy; Richard S. Miller | Zendy; Brian G. Harbrecht | Zendy; Jeffrey A. Claridge | Zendy; Herb A. Phelan | Zendy; Matthew D. Neal | Zendy; Brian S. Zuckerbraun | Zendy; Mark H. Yazer | Zendy; Timothy R. Billiar | Zendy; Jason L. Sperry | Zendy

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Association of Prehospital Plasma With Survival in Patients With Traumatic Brain Injury

Author(s) -

Danielle S. Gruen,

Francis X. Guyette,

Joshua B. Brown,

David O. Okonkwo,

Ava M. Puccio,

Insiyah Campwala,

Matthew T. Tessmer,

Brian J. Daley,

Richard S. Miller,

Brian G. Harbrecht,

Jeffrey A. Claridge,

Herb A. Phelan,

Matthew D. Neal,

Brian S. Zuckerbraun,

Mark H. Yazer,

Timothy R. Billiar,

Jason L. Sperry

Publication year - 2020

Publication title -

jama network open

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.278

H-Index - 39

ISSN - 2574-3805

DOI - 10.1001/jamanetworkopen.2020.16869

Subject(s) - medicine , traumatic brain injury , interquartile range , randomized controlled trial , hazard ratio , emergency medicine , subgroup analysis , resuscitation , emergency medical services , confidence interval , psychiatry

Key Points Question Is prehospital plasma administration associated with improved survival among severely injured patients with traumatic brain injury (TBI)? Findings In this secondary analysis of a predefined subgroup of 166 severely injured patients with trauma from a cluster randomized clinical trial, prehospital plasma administration was associated with lower mortality in patients with TBI. Meaning Future studies are needed to confirm these clinical benefits, but prehospital plasma administered soon after injury may improve survival for patients with TBI.

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