Association of Alcohol-Induced Loss of Consciousness and Overall Alcohol Consumption With Risk for Dementia | Zendy

Mika Kivimäki | Zendy; Archana SinghManoux | Zendy; G. David Batty | Zendy; Séverine Sabia | Zendy; Andrew Sommerlad | Zendy; Sarah Floud | Zendy; Markus Jokela | Zendy; Jussi Vahtera | Zendy; May A. Beydoun | Zendy; Sakari Suominen | Zendy; Aki Koskinen | Zendy; Ari Väänänen | Zendy; Marcel Goldberg | Zendy; Marie Zins | Zendy; Lars Alfredsson | Zendy; Peter Westerholm | Zendy; Anders Knutsson | Zendy; Solja T. Nyberg | Zendy; Pyry N. Sipilä | Zendy; Joni V. Lindbohm | Zendy; Jaana Pentti | Zendy; Gill Livingston | Zendy; Jane E. Ferrie | Zendy; Timo Strandberg | Zendy

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Association of Alcohol-Induced Loss of Consciousness and Overall Alcohol Consumption With Risk for Dementia

Author(s) -

Mika Kivimäki,

Archana SinghManoux,

G. David Batty,

Séverine Sabia,

Andrew Sommerlad,

Sarah Floud,

Markus Jokela,

Jussi Vahtera,

May A. Beydoun,

Sakari Suominen,

Aki Koskinen,

Ari Väänänen,

Marcel Goldberg,

Marie Zins,

Lars Alfredsson,

Peter Westerholm,

Anders Knutsson,

Solja T. Nyberg,

Pyry N. Sipilä,

Joni V. Lindbohm,

Jaana Pentti,

Gill Livingston,

Jane E. Ferrie,

Timo Strandberg

Publication year - 2020

Publication title -

jama network open

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.278

H-Index - 39

ISSN - 2574-3805

DOI - 10.1001/jamanetworkopen.2020.16084

Subject(s) - dementia , medicine , confounding , hazard ratio , cohort study , population , alcohol consumption , cohort , gerontology , alcohol , demography , environmental health , confidence interval , disease , biochemistry , chemistry , sociology

Key Points Question Are alcohol-induced loss of consciousness and heavy weekly alcohol consumption associated with increased risk of future dementia? Findings In this multicohort study of 131 415 adults, a 1.2-fold excess risk of dementia was associated with heavy vs moderate alcohol consumption. Those who reported having lost consciousness due to alcohol consumption, regardless of their overall weekly consumption, had a 2-fold increased risk of dementia compared with people who had not lost consciousness and were moderate drinkers. Meaning The findings of this study suggest that alcohol-induced loss of consciousness is a long-term risk factor for dementia among both heavy and moderate drinkers.

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