Plasma Biomarker Concentrations Associated With Return to Sport Following Sport-Related Concussion in Collegiate Athletes—A Concussion Assessment, Research, and Education (CARE) Consortium Study | Zendy

C. Pattinson | Zendy; Timothy B. Meier | Zendy; Vivian A. Guedes | Zendy; Chen Lai | Zendy; Christina Devoto | Zendy; Thaddeus Haight | Zendy; Steven P. Broglio | Zendy; Thomas W. McAllister | Zendy; Christopher C. Giza | Zendy; Daniel L. Huber | Zendy; Jaroslaw Harezlak | Zendy; Kenneth L. Cameron | Zendy; Gerald McGinty | Zendy; Jonathan Jackson | Zendy; Kevin M. Guskiewicz | Zendy; Jason P. Mihalik | Zendy; Alison Brooks | Zendy; Stefan M. Duma | Zendy; Steven Rowson | Zendy; Lindsay D. Nelson | Zendy; Paul F. Pasquina | Zendy; Michael McCrea | Zendy; Jessica Gill | Zendy

Open Access

Plasma Biomarker Concentrations Associated With Return to Sport Following Sport-Related Concussion in Collegiate Athletes—A Concussion Assessment, Research, and Education (CARE) Consortium Study

Author(s) -

C. Pattinson,

Timothy B. Meier,

Vivian A. Guedes,

Chen Lai,

Christina Devoto,

Thaddeus Haight,

Steven P. Broglio,

Thomas W. McAllister,

Christopher C. Giza,

Daniel L. Huber,

Jaroslaw Harezlak,

Kenneth L. Cameron,

Gerald McGinty,

Jonathan Jackson,

Kevin M. Guskiewicz,

Jason P. Mihalik,

Alison Brooks,

Stefan M. Duma,

Steven Rowson,

Lindsay D. Nelson,

Paul F. Pasquina,

Michael McCrea,

Jessica Gill

Publication year - 2020

Publication title -

jama network open

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.278

H-Index - 39

ISSN - 2574-3805

DOI - 10.1001/jamanetworkopen.2020.13191

Subject(s) - concussion , athletes , biomarker , medicine , physical therapy , psychology , physical medicine and rehabilitation , injury prevention , poison control , medical emergency , biology , biochemistry

Key Points Question Are plasma biomarkers associated with a return-to-sport period of less than 14 days vs 14 days or more in male and female collegiate athletes following a sport-related concussion? Findings This diagnostic study, which included 127 collegiate athletes who had sustained a sports-related concussion, found that higher total tau concentrations 24 to 48 hours after injury and at the time of symptom resolution as well as lower glial fibrillary acidic protein levels acutely postinjury were associated with return-to-sport decisions. Meaning In this study, total tau and glial fibrillary acidic protein levels were associated with return to sport in male and female collegiate athletes following a sports-related concussion.

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