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Assessment of Nonradioactive Multispectral Optoacoustic Tomographic Imaging With Conventional Lymphoscintigraphic Imaging for Sentinel Lymph Node Biopsy in Melanoma
Author(s) -
Ingo Stoffels,
Philipp Jansen,
Maximilian Petri,
Lukas Goerdt,
Titus J. Brinker,
Klaus Griewank,
Thorsten D. Poeppel,
Dirk Schadendorf,
Joachim Klode
Publication year - 2019
Publication title -
jama network open
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.278
H-Index - 39
ISSN - 2574-3805
DOI - 10.1001/jamanetworkopen.2019.9020
Subject(s) - medicine , sentinel lymph node , indocyanine green , nuclear medicine , lymph , biopsy , radiology , melanoma , gamma probe , multispectral image , technetium , scintigraphy , breast cancer , pathology , cancer , cancer research , computer science , computer vision
Key Points Question Is a nonradioactive imaging approach for sentinel lymph node detection a viable alternative to radioactive technetium? Findings In this cross-sectional study of 83 patients with newly diagnosed melanoma, sentinel lymph node detection via indocyanine green and multispectral optoacoustic tomographic imaging was concordant with the detection frequency of conventional lymphoscintigraphic imaging with technetium Tc 99m. Meaning Multispectral optoacoustic tomographic imaging may allow nonradioactive detection of sentinel lymph nodes at a frequency similar to the current radiotracer standard.

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