Development and Validation of a Bedside Risk Assessment for Sustained Prescription Opioid Use After Surgery
Author(s) -
Muhammad Ali Chaudhary,
Nizar Bhulani,
E De Jager,
Stuart R. Lipsitz,
Nicollette K. Kwon,
Daniel J. Sturgeon,
QuocDien Trinh,
Tracey Koehlmoos,
Adil H. Haider,
Andrew J. Schoenfeld
Publication year - 2019
Publication title -
jama network open
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.278
H-Index - 39
ISSN - 2574-3805
DOI - 10.1001/jamanetworkopen.2019.6673
Subject(s) - medicine , opioid , medical prescription , intensive care medicine , risk assessment , pharmacology , computer science , computer security , receptor
Key Points Question Can a risk score for sustained prescription opioid use after surgery be developed for a working-age population using readily available clinical information? Findings In this case-control study of 86 356 patients undergoing 1 of 10 common surgical procedures, prior opioid exposure was the factor most strongly associated with sustained opioid use. The group with the lowest Stopping Opioids After Surgery scores (<31) had a mean 4.1% risk of sustained opioid use; the group with intermediate scores (31-50) had a mean risk of 14.9%; and the group with the highest scores (>50) had a mean risk of 35.8%. Meaning The scoring system developed in this study may inform the risk of sustained prescription opioid use after surgery and be scalable to clinical practice.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom