Association of Estimated Long-term Exposure to Air Pollution and Traffic Proximity With a Marker for Coronary Atherosclerosis in a Nationwide Study in China | Zendy

Meng Wang | Zendy; Zhihui Hou | Zendy; Hao Xu | Zendy; Yang Liu | Zendy; Matthew J. Budoff | Zendy; Adam A. Szpiro | Zendy; Joel D. Kaufman | Zendy; Sverre Vedal | Zendy; Bin Lü | Zendy

Open Access

Association of Estimated Long-term Exposure to Air Pollution and Traffic Proximity With a Marker for Coronary Atherosclerosis in a Nationwide Study in China

Author(s) -

Meng Wang,

Zhihui Hou,

Hao Xu,

Yang Liu,

Matthew J. Budoff,

Adam A. Szpiro,

Joel D. Kaufman,

Sverre Vedal,

Bin Lü

Publication year - 2019

Publication title -

jama network open

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.278

H-Index - 39

ISSN - 2574-3805

DOI - 10.1001/jamanetworkopen.2019.6553

Subject(s) - medicine , myocardial infarction , air pollution , population , coronary artery disease , prospective cohort study , environmental health , cardiology , chemistry , organic chemistry

Key Points Question Are long-term exposure to ambient air pollution and proximity to traffic associated with subclinical atherosclerosis? Findings In this population-based cross-sectional study of 8867 Chinese participants, long-term exposure to ambient nitrogen dioxide and fine particulate matter with aerodynamic diameter less than 2.5 μm was independently associated with a higher coronary artery calcium score, a key atherosclerotic marker. Associations with ozone and proximity to traffic were less consistent. Meaning Long-term exposure to ambient air pollution may be an important risk factor for coronary atherosclerosis.

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