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Long-term Effects of Multimodal Treatment on Adult Attention-Deficit/Hyperactivity Disorder Symptoms
Author(s) -
Alexandra P. Lam,
Swantje Matthies,
Erika Graf,
Michael Colla,
Christian Jacob,
Esther Sobanski,
Barbara Alm,
Michael Rösler,
Wolfgang Retz,
Petra RetzJunginger,
Bernhard Kis,
Mona AbdelHamid,
Helge Müller,
Caroline Lücke,
Michael Huß,
Thomas Jans,
Thomas Berger,
Ludger Tebartz van Elst,
Alexandra Philipsen
Publication year - 2019
Publication title -
jama network open
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.278
H-Index - 39
ISSN - 2574-3805
DOI - 10.1001/jamanetworkopen.2019.4980
Subject(s) - term (time) , attention deficit hyperactivity disorder , psychology , attention deficit , attention deficit disorder , cognitive psychology , psychiatry , physics , quantum mechanics
Key Points Question What are the long-term results of multimodal treatment for adult attention-deficit/hyperactivity disorder (ADHD) when comparing cognitive behavioral group psychotherapy (GPT) with individual clinical management (CM) in combination with either methylphenidate or placebo? Findings In this follow-up assessment of the Comparison of Methylphenidate and Psychotherapy in Adult ADHD Study (COMPAS), a multicenter randomized clinical trial, 256 adults participated in follow-up 1.5 years after the intervention ended. The severity of ADHD symptoms improved in all 4 prior treatment groups, with no significant difference found between GPT and CM, but methylphenidate was associated with a larger improvement in symptoms compared with placebo. Meaning Results from the COMPAS trial demonstrate an improvement of ADHD symptoms over 1.5 years in adults with ADHD after 1 year of treatment with methylphenidate plus either GPT or CM.

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