Correlation of Milestone Restricted Mean Survival Time Ratio With Overall Survival Hazard Ratio in Randomized Clinical Trials of Immune Checkpoint Inhibitors | Zendy

Zixian Wang | Zendy; HaoXiang Wu | Zendy; Li Xie | Zendy; Ying-Nan Wang | Zendy; Lu-Ping Yang | Zendy; Ming-Ming He | Zendy; Hui Luo | Zendy; Pei-Rong Ding | Zendy; Dan Xie | Zendy; Gong Chen | Zendy; Yu-Hong Li | Zendy; Feng Wang | Zendy; RuiHua Xu | Zendy

Open Access

Correlation of Milestone Restricted Mean Survival Time Ratio With Overall Survival Hazard Ratio in Randomized Clinical Trials of Immune Checkpoint Inhibitors

Author(s) -

Zixian Wang,

HaoXiang Wu,

Li Xie,

Ying-Nan Wang,

Lu-Ping Yang,

Ming-Ming He,

Hui Luo,

Pei-Rong Ding,

Dan Xie,

Gong Chen,

Yu-Hong Li,

Feng Wang,

RuiHua Xu

Publication year - 2019

Publication title -

jama network open

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.278

H-Index - 39

ISSN - 2574-3805

DOI - 10.1001/jamanetworkopen.2019.3433

Subject(s) - milestone , hazard ratio , medicine , confidence interval , clinical trial , randomized controlled trial , proportional hazards model , survival analysis , cartography , geography

This systematic review and meta-analysis examines randomized clinical trials (RCTs) of immune checkpoint inhibitors to evaluate the use of milestone rate and milestone restricted mean survival time as intermediate end points in immune checkpoint inhibitor trials.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research