Open AccessClinical Characteristics of and Risk Factors for Chronic Kidney Disease Among Adults and Children
Author(s) -
Katherine R. Tuttle,
Radica Z. Alicic,
O. Kenrik Duru,
Cami R. Jones,
Kenn B. Daratha,
Susanne B. Nicholas,
Sterling McPherson,
Joshua J. Neumiller,
Douglas S. Bell,
Carol M. Mangione,
Keith C. Norris
Publication year - 2019
Publication title -
jama network open
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.278
H-Index - 39
ISSN - 2574-3805
DOI - 10.1001/jamanetworkopen.2019.18169
Subject(s) - medicine , kidney disease , interquartile range , prediabetes , diabetes mellitus , cohort , renal function , pediatrics , type 2 diabetes , endocrinology
Key Points Question What are the clinical characteristics of and major risk factors for chronic kidney disease among patients in 2 large US health care systems? Findings In this cohort study of the Center for Kidney Research, Education, and Hope (CURE-CKD) registry, more than 2.6 million adults and children had chronic kidney disease or were at risk. Albuminuria or proteinuria was tested in approximately one-eighth of adults with chronic kidney disease, renin-angiotensin system inhibitors were prescribed to one-fifth, and nonsteroidal anti-inflammatory agents or proton pump inhibitors were prescribed to more than one-third. Meaning Despite common occurrence of chronic kidney disease, rates of identification and use of kidney protective agents were low, while use of potential nephrotoxins was widespread.
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