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Simulation of Health and Economic Benefits of Extended Observation of Resolved Anaphylaxis
Author(s) -
Marcus Shaker,
Dana Wallace,
David B.K. Golden,
John Oppenheimer,
Matthew Greenhawt
Publication year - 2019
Publication title -
jama network open
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.278
H-Index - 39
ISSN - 2574-3805
DOI - 10.1001/jamanetworkopen.2019.13951
Subject(s) - anaphylaxis , medicine , allergy , emergency medicine , immunology
Key Points Question What is the cost-effectiveness of 1 hour vs 6 to 24 hours of medical observation for biphasic anaphylaxis? Findings In this economic evaluation, routine use of prolonged medical observation costs $62 374 to $230 202 per case of biphasic anaphylaxis observed, depending on the hourly costs of observation and duration of stay, with costs of prolonged observation approaching or exceeding $10 million per death prevented. Meaning Routine use of 6- to 24-hour medical observation for unselected patients with resolved anaphylaxis is a low-value medical practice unless the risk of biphasic anaphylaxis is significantly pronounced.

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