Association of Exposure to Ambient Air Pollution With Thyroid Function During Pregnancy | Zendy

Akhgar Ghassabian | Zendy; Livia Pierotti | Zendy; Mikel Basterrechea | Zendy; Leda Chatzi | Zendy; Marisa Estarlich | Zendy; Ana FernándezSomoano | Zendy; Abby F. Fleisch | Zendy; Diane R. Gold | Zendy; Jordi Júlvez | Zendy; Polyxeni Karakosta | Zendy; Aitana Lertxundi | Zendy; María-José López-Espinosa | Zendy; Tessa A. Mulder | Zendy; Tim I.M. Korevaar | Zendy; Emily Oken | Zendy; Robin P. Peeters | Zendy; Sheryl L. RifasShiman | Zendy; Euripides G. Stephanou | Zendy; Adonina Tardón | Zendy; Henning Tiemeier | Zendy; Martine Vrijheid | Zendy; Tanja G. M. Vrijkotte | Zendy; Jordi Sunyer | Zendy; Mònica Guxens | Zendy

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Association of Exposure to Ambient Air Pollution With Thyroid Function During Pregnancy

Author(s) -

Akhgar Ghassabian,

Livia Pierotti,

Mikel Basterrechea,

Leda Chatzi,

Marisa Estarlich,

Ana FernándezSomoano,

Abby F. Fleisch,

Diane R. Gold,

Jordi Júlvez,

Polyxeni Karakosta,

Aitana Lertxundi,

María-José López-Espinosa,

Tessa A. Mulder,

Tim I.M. Korevaar,

Emily Oken,

Robin P. Peeters,

Sheryl L. RifasShiman,

Euripides G. Stephanou,

Adonina Tardón,

Henning Tiemeier,

Martine Vrijheid,

Tanja G. M. Vrijkotte,

Jordi Sunyer,

Mònica Guxens

Publication year - 2019

Publication title -

jama network open

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.278

H-Index - 39

ISSN - 2574-3805

DOI - 10.1001/jamanetworkopen.2019.12902

Subject(s) - medicine , thyroid function , pregnancy , thyroid , thyroid function tests , cohort , thyroid peroxidase , cohort study , obstetrics , biology , genetics

Key Points Question Is exposure to ambient air pollution in the first trimester associated with thyroid function throughout pregnancy? Findings Among 9931 pregnant women in 4 European cohorts and 1 US cohort, an increase of 5 μg/m 3 in exposure to particulate matter with an aerodynamic diameter of 2.5 μm or less was associated with 20% higher odds of hypothyroxinemia. Meaning The findings of this study raise the possibility that exposure to particulate matter might disrupt thyroid function in pregnant women.

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