Evaluation of Oxygen Saturation Index Compared With Oxygenation Index in Neonates With Hypoxemic Respiratory Failure | Zendy

Hemananda Muniraman | Zendy; Ashley Song | Zendy; Rangasamy Ramanathan | Zendy; Kathryn L. Fletcher | Zendy; Rutuja Kibe | Zendy; Li Ding | Zendy; Ashwini Lakshmanan | Zendy; Manoj Biniwale | Zendy

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Evaluation of Oxygen Saturation Index Compared With Oxygenation Index in Neonates With Hypoxemic Respiratory Failure

Author(s) -

Hemananda Muniraman,

Ashley Song,

Rangasamy Ramanathan,

Kathryn L. Fletcher,

Rutuja Kibe,

Li Ding,

Ashwini Lakshmanan,

Manoj Biniwale

Publication year - 2019

Publication title -

jama network open

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.278

H-Index - 39

ISSN - 2574-3805

DOI - 10.1001/jamanetworkopen.2019.1179

Subject(s) - interquartile range , medicine , gestational age , mechanical ventilation , cohort , oxygen saturation , respiratory failure , oxygenation , oxygenation index , predictive value of tests , anesthesia , pregnancy , oxygen , chemistry , genetics , organic chemistry , biology

Key Points Question Is oxygen saturation index (OSI) a reliable surrogate marker of oxygenation index (OI) in neonates with hypoxemic respiratory failure? Findings In this cohort study including 1442 paired OI and OSI measurements from 220 neonates, OSI was noted to correlate strongly with OI. Derived OI from OSI was in good agreement and strongly predictive of clinically relevant OI cutoffs from 5 to 25. Meaning Derived OI from noninvasive measurements may be useful to reliably assess severity of respiratory illness and response to therapy on a continuous basis.

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