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Association of Diabetes With Central Corneal Thickness Among a Multiethnic Asian Population
Author(s) -
Xiao-Yang Luo,
Wei Dai,
Miao-Li Chee,
Yijin Tao,
Jacqueline Chua,
Nicholas Tan,
YihChung Tham,
Tin Aung,
Tien Yin Wong,
ChingYu Cheng
Publication year - 2019
Publication title -
jama network open
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.278
H-Index - 39
ISSN - 2574-3805
DOI - 10.1001/jamanetworkopen.2018.6647
Subject(s) - medicine , diabetes mellitus , ophthalmology , glycated hemoglobin , population , intraocular pressure , glaucoma , type 2 diabetes , environmental health , endocrinology
Key Points Question Are diabetes status, random glucose, and hemoglobin A 1c associated with central corneal thickness (CCT) measurement? Findings In this cross-sectional study of 8846 multiethnic Asian adults, diabetes and glucose and hemoglobin A 1c levels were associated with thicker CCT; these associations were significant in the subgroup with diabetes but not in the subgroup without diabetes. A meta-analysis including 12 previous studies showed that CCT was 12.8 μm thicker in eyes of patients with diabetes. Meaning Findings from this study are important for CCT determination and may provide useful information on the interpretation of intraocular pressure in patients with diabetes.

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