Association of Prenatal Ultrasonographic Findings With Adverse Neonatal Outcomes Among Pregnant Women With Zika Virus Infection in Brazil | Zendy

José Paulo Pereira | Zendy; Karin NielsenSaines | Zendy; Jeffrey D. Sperling | Zendy; Melanie Maykin | Zendy; Luana Damasceno | Zendy; Renan Fonseca Cardozo | Zendy; Helena Abreu Valle | Zendy; Beatriz Ribeiro Torres Dutra | Zendy; Helder Dotta Gama | Zendy; Kristina Adachi | Zendy; Andréa Zin | Zendy; Irena Tsui | Zendy; Zilton Vasconcelos | Zendy; Patrícia Brasil | Zendy; Maria Elizabeth Lopes Moreira | Zendy; Stephanie L. Gaw | Zendy

Open Access

Association of Prenatal Ultrasonographic Findings With Adverse Neonatal Outcomes Among Pregnant Women With Zika Virus Infection in Brazil

Author(s) -

José Paulo Pereira,

Karin NielsenSaines,

Jeffrey D. Sperling,

Melanie Maykin,

Luana Damasceno,

Renan Fonseca Cardozo,

Helena Abreu Valle,

Beatriz Ribeiro Torres Dutra,

Helder Dotta Gama,

Kristina Adachi,

Andréa Zin,

Irena Tsui,

Zilton Vasconcelos,

Patrícia Brasil,

Maria Elizabeth Lopes Moreira,

Stephanie L. Gaw

Publication year - 2018

Publication title -

jama network open

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.278

H-Index - 39

ISSN - 2574-3805

DOI - 10.1001/jamanetworkopen.2018.6529

Subject(s) - medicine , zika virus , pregnancy , obstetrics , microcephaly , pediatrics , odds ratio , interquartile range , gestational age , cohort study , prenatal diagnosis , prospective cohort study , fetus , immunology , virus , genetics , biology

Key Points Question Are prenatal ultrasonographic findings in maternal Zika virus infection associated with adverse neonatal outcomes? Findings In this cohort study of 92 women with confirmed Zika virus infection in pregnancy, 37 had an abnormal result on prenatal ultrasonography that was associated with adverse composite neonatal outcomes. However, 23 of 55 neonates who had normal results on prenatal ultrasonography still had adverse neonatal outcomes. Meaning Abnormal results on prenatal ultrasonography are associated with adverse neonatal outcomes; however, a comprehensive neonatal evaluation is recommended for all infants with suspected in utero Zika exposure.

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