Association Between Obesity and Cardiovascular Outcomes | Zendy

Haris Riaz | Zendy; Muhammad Shahzeb Khan | Zendy; Tariq Jamal Siddiqi | Zendy; Muhammad Usman | Zendy; Nishant Shah | Zendy; Amit Goyal | Zendy; Sadiya S. Khan | Zendy; Farouk Mookadam | Zendy; Richard A. Krasuski | Zendy; Haitham M. Ahmed | Zendy

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Association Between Obesity and Cardiovascular Outcomes

Author(s) -

Haris Riaz,

Muhammad Shahzeb Khan,

Tariq Jamal Siddiqi,

Muhammad Usman,

Nishant Shah,

Amit Goyal,

Sadiya S. Khan,

Farouk Mookadam,

Richard A. Krasuski,

Haitham M. Ahmed

Publication year - 2018

Publication title -

jama network open

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.278

H-Index - 39

ISSN - 2574-3805

DOI - 10.1001/jamanetworkopen.2018.3788

Subject(s) - medicine , mendelian randomization , meta analysis , confounding , observational study , population , odds ratio , obesity , environmental health , biology , biochemistry , genetic variants , gene , genotype

Key Points Question Do mendelian randomization data show that an association exists between obesity and cardiovascular outcomes? Findings In this systematic review and meta-analysis of nearly 1 million participants, obesity was associated with type 2 diabetes and coronary artery disease but not with stroke. Meaning Obesity may increase the risk of subsequent diabetes and may contribute to cardiovascular outcomes and should thus remain a major focus of public health initiatives.

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