Association of Antenatal Steroid Exposure With Survival Among Infants Receiving Postnatal Life Support at 22 to 25 Weeks’ Gestation | Zendy

Danielle Ehret | Zendy; Erika M. Edwards | Zendy; Lucy T. Greenberg | Zendy; Ira M. Bernstein | Zendy; Jeffrey S. Buzas | Zendy; Roger F. Soll | Zendy; Jeffrey D. Horbar | Zendy

Open Access

Association of Antenatal Steroid Exposure With Survival Among Infants Receiving Postnatal Life Support at 22 to 25 Weeks’ Gestation

Author(s) -

Danielle Ehret,

Erika M. Edwards,

Lucy T. Greenberg,

Ira M. Bernstein,

Jeffrey S. Buzas,

Roger F. Soll,

Jeffrey D. Horbar

Publication year - 2018

Publication title -

jama network open

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.278

H-Index - 39

ISSN - 2574-3805

DOI - 10.1001/jamanetworkopen.2018.3235

Subject(s) - gestation , medicine , antenatal steroid , association (psychology) , obstetrics , pregnancy , pediatrics , psychology , biology , genetics , psychotherapist

Key Points Question For infants born at the edge of viability who received postnatal life support, was the administration of antenatal steroids associated with higher rates of survival? Finding In a cohort study of 33 472 infants born at 22 to 25 weeks’ gestation between 2012 and 2016, the concordant receipt of antenatal steroids and postnatal life support was significantly associated with higher rates of survival compared with postnatal life support alone. Meaning There is an opportunity for reevaluation of national guidelines, allowing for shared decision making with concordant obstetrical and neonatal treatment plans.

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