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Adolescent Cognitive Aptitudes and Later-in-Life Alzheimer Disease and Related Disorders
Author(s) -
Alison Huang,
Kiersten L. Strombotne,
Elizabeth Mokyr Horner,
Susan Lapham
Publication year - 2018
Publication title -
jama network open
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.278
H-Index - 39
ISSN - 2574-3805
DOI - 10.1001/jamanetworkopen.2018.1726
Subject(s) - dementia , odds ratio , gerontology , cognition , odds , medicine , socioeconomic status , population , cohort , cognitive skill , cohort study , disease , psychology , logistic regression , demography , clinical psychology , psychiatry , environmental health , sociology
Key Points Question What are the associations between specific adolescent cognitive abilities and Alzheimer disease and related disorders in later life? Findings In this cohort study of 43 014 men and 42 749 women, lower adolescent memory for words, in women, and lower mechanical reasoning, in men, were associated with higher odds of Alzheimer disease and related disorders in later life. Meaning Low performance on certain specific measures of cognitive ability may indicate future risk of Alzheimer disease and related disorders as early as adolescence.

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