Association of Mortality and Acute Aortic Events With Ascending Aortic Aneurysm | Zendy

Ming Hao Guo | Zendy; Jehangir J. Appoo | Zendy; Richard Saczkowski | Zendy; Holly N. Smith | Zendy; Maral Ouzounian | Zendy; Alexander J. Gregory | Zendy; Eric Herget | Zendy; Munir Boodhwani | Zendy

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Association of Mortality and Acute Aortic Events With Ascending Aortic Aneurysm

Author(s) -

Ming Hao Guo,

Jehangir J. Appoo,

Richard Saczkowski,

Holly N. Smith,

Maral Ouzounian,

Alexander J. Gregory,

Eric Herget,

Munir Boodhwani

Publication year - 2018

Publication title -

jama network open

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.278

H-Index - 39

ISSN - 2574-3805

DOI - 10.1001/jamanetworkopen.2018.1281

Subject(s) - cardiology , medicine , aortic aneurysm , aneurysm , association (psychology) , surgery , aorta , psychology , psychotherapist

Key Points Question What are the growth rate and risk of complications in patients with moderately dilated ascending aortas? Findings This systematic review and meta-analysis of 20 studies including 8800 patients found that the ascending aorta growth rate was 0.61 mm/y, and the incidence of elective aortic surgery was 13.82%. The linearized mortality rate was 1.99% per patient-year, while the rate of aortic dissection, aortic rupture, and mortality was 2.16% per patient-year. Meaning More robust natural history data from prospective studies are needed to better inform clinical decision making in patients with ascending aortic aneurysms.

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