Prestroke and Poststroke Antithrombotic Therapy in Patients With Atrial Fibrillation | Zendy

Anna Gundlund | Zendy; Ying Xian | Zendy; Eric D. Peterson | Zendy; Jawad H. Butt | Zendy; Kasper Gadsbøll | Zendy; Jonas Bjerring Olesen | Zendy; Lars Køber | Zendy; Christian TorpPedersen | Zendy; Gunnar Gislason | Zendy; Emil Loldrup Fosbøl | Zendy

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Prestroke and Poststroke Antithrombotic Therapy in Patients With Atrial Fibrillation

Author(s) -

Anna Gundlund,

Ying Xian,

Eric D. Peterson,

Jawad H. Butt,

Kasper Gadsbøll,

Jonas Bjerring Olesen,

Lars Køber,

Christian TorpPedersen,

Gunnar Gislason,

Emil Loldrup Fosbøl

Publication year - 2018

Publication title -

jama network open

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.278

H-Index - 39

ISSN - 2574-3805

DOI - 10.1001/jamanetworkopen.2018.0171

Subject(s) - medicine , interquartile range , antithrombotic , stroke (engine) , atrial fibrillation , retrospective cohort study , cohort study , cohort , warfarin , medical prescription , cardiology , physical therapy , pediatrics , mechanical engineering , engineering , pharmacology

Key Points Question Is oral anticoagulation therapy used and effective for secondary stroke prophylaxis in patients with atrial fibrillation? Findings In this cohort study of 30 626 intermediate- to high-risk patients with atrial fibrillation having an ischemic stroke, 36.3% received oral anticoagulation therapy before their stroke, and 52.5% received oral anticoagulation therapy after their stroke. Oral anticoagulation therapy was associated with a statistically significant reduction in thromboembolic risk. Meaning There exists a major potential for optimization of both primary and secondary stroke prophylaxis in patients with atrial fibrillation.

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