Association of Ticagrelor vs Clopidogrel With Major Adverse Coronary Events in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention
Author(s) -
Ricky D. Turgeon,
Sheri L. Koshman,
Erik Youngson,
Bryan Har,
Stephen B. Wilton,
Matthew T. James,
Michelle M. Graham
Publication year - 2020
Publication title -
jama internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.14
H-Index - 342
eISSN - 2168-6114
pISSN - 2168-6106
DOI - 10.1001/jamainternmed.2019.6447
Subject(s) - medicine , ticagrelor , clopidogrel , acute coronary syndrome , percutaneous coronary intervention , mace , conventional pci , cardiology , population , aspirin , myocardial infarction , environmental health
Guidelines currently recommend ticagrelor over clopidogrel for patients with acute coronary syndrome (ACS) based on randomized clinical trial data in which ticagrelor reduced major adverse coronary events (MACE) vs clopidogrel but increased bleeding and dyspnea.
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